Sid Meier's Pirates! won't install?

I recently dusted off my copy of Sid Meier's Pirates! (2004 Remake.) I loved playing this game when I was younger and strongly desire to start up again. However, when I try to install it, I get a little window popping up the says "1607: Unable to install InstallShield Scripting Runtime". I have already tried to install ISScript8.msi, but it gives me an Error 1500. I have already deleted "InProgress" from the registry. I am honestly at a loss on what to do from here. My computer geekiness only goes so far, I'm afraid. Thanks for the help folks!